Open Access Open Access  Restricted Access Subscription or Fee Access

Chromatographic Fingerprint Analysis and Bioactivity of Origanum Vulgare Extracts

Corina Bubueanu, Ioana Nicu, Lucia Pirvu


A very important measure for any country, in terms of public health problems and commercial exploitation, must be the development of medicinal and aromatic plant resources. Long-term strategies for the conservation of medicinal and aromatic plants, personnel training, cultivation or passage in culture of valuable species, sustainable methods of harvesting and processing plants to promote scientific research and validation of traditional remedies are needed. In the present, the natural compounds research are mainly focused on their role in improving health.  The extraction processes of the natural compound are significant both in scientific and economic terms. The goal is to obtain extracts with pharmacological activity with a minimum production cost.

In this paper are analyzed hot and cold ethanol 50 % extracts of Origanum vulgare (Fam. Lamiaceae) species in terms of qualitative and quantitative chemical composition, and their antioxidant and antimicrobial potential.

The results obtained showed no significant differences in terms of chemical composition and bioactivity, between the extracts. Thus, in industry sector these results can be used for reducing cost production.





Hot extract, cold extract, Origanum vulgare, industry

Full Text:



Bendini A., Gallina T. Toschi and G. Lercker 2002. Antioxidant activity of oregano (Origanum vulgare L.) leaves, Ital. J. Food Sci. n. 1, vol. 14

Cervato Giovanna, Carabelli Marta, Gervasio Silvia, Cittera Andrea, Cazzola Roberta and Cestaro Benvenuto, 2000. Antioxidant properties of Oregano (Origanum vulgare) leaf extracts- Journal of Food Biochemistry 24, 453-465;

European Pharmacopoeia 6,0

Huang DJ, Ou BX, Prior RL. 2005 The chemistry behind antioxidant capacity assays. J Agric Food Chem;53:1841-1856

Mancini E, Camele I, Elshafie HS, De Martino L, Pellegrino C, Grulova D, DeFeo V, 2014. Chemical composition and biological activity of the essential oil of Origanum vulgare ssp. hirtum from different areas in the Southern Apennines (Italy).Chem Biodivers. Apr;11(4):639-51

Miller AB, Cates RG, Lawrence M, Soria JA, Espinoza LV, Martinez JV, Arbizú DA, 2014. The antibacterial and antifungal activity of essential oils extracted from Guatemalan medicinal plants.Pharm Biol. Oct 21:1-7;

Parvu Constantin 1997. Universul plantelor Mica enciclopedie – Ed. Enciclopedica , Bucuresti

Prieto P., Pineda M., Aquilar M. 1999. Spectrophotometric quantitation of antioxidant capacity through the formation of a phosphomolybdenum complex: specific application to the determination of vitamin E. //Analytical Biochemistry, p. 337-341

Radusiene Jolita, Ivanauskas Liudas, Janulis Valdimaras, Jakstas Valdas, 2008. Composition and variability of phenolic compounds in Origanum vulgare from Lithuania. Biologija. Vol. 54. Nr. 1. P. 45–49;

Sanchez-Moreno, C. Larrauri, J.A., Saura-Calixto, F., 1998. A procedure to measure the antiradical efficiency of polyphenols. Journal of Agricultural and Food Chemistry 76, 270-276

Teixeira Barbara, Antonio Marques, Cristina Ramos, Carmo Serrano, Olivia Matos, Nuno R Neng, Jose M. F. Nogueira, Jorge Alexandre Saraiva and Maria Leonor Nunes, 2013. Chemical composition and bioactivity of different oregano (Origanum vulgare) extracts and essential oil. J Sci Food Agric 93 (11): 2707–2714;

Wagner H., Bladt S., 1996. Plant Drug Analysis, Second Edition, Springer.

-- 0 --


  • There are currently no refbacks.

Copyright (c) 2016 Corina Bubueanu, Ioana Nicu, Lucia Pirvu

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.