Antimicrobial Study of Oil and Stem Bark Extracts of Pentaclethra Macrophylla Benth on Six Selected Pathogens

Authors

  • A. M. Yusuf Babatunde Ogun State College of Health Technology
  • L. S. Kasim Olabisi Onabanjo University
  • Adegbite A. Ayoade Ogun State College of Health Technology

DOI:

https://doi.org/10.18034/mjmbr.v3i1.399

Keywords:

Pentaclethra macrophylla benth, antimicrobial, clinical isolates

Abstract

The antimicrobial activity of oil and stem bark extracts of pentaclethra macrophylla benth was determined against staphylococcus aureus, streptococcus pneumonia, Eschericia coli, Haemophilus influenza, α-Haemolytic Streptococcus and Yeast, using hole diffusion method. The results revealed that the most inhibitory zone (25.0mm) was recorded in hexane oil extract against staphylococcus aureus and α-Haemolytic Streptococcus. The minimum inhibitory concentration (MIC) of the oil extract ranges between 7.8125-62.5mg/ml on all the test organisms and aqueous stem bark extract inhibited only Eschericia coli with minimum, inhibitory concentration (MIC) of 62.5mg/ml. However, the oil extract possessed more antimicrobial activity than the stem bark extract. These findings lend more knowledge to the use of pentaclethra macrophylla benth for medicinal purposes.

 

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Author Biographies

  • A. M. Yusuf Babatunde, Ogun State College of Health Technology

    Department of Pharmaceutical Technology, Ogun State College of Health Technology, Ilese-Ijebu, NIGERIA

  • L. S. Kasim, Olabisi Onabanjo University

    Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmacy, Olabisi Onabanjo University, Sagamu Campus, Ogun State, NIGERIA

  • Adegbite A. Ayoade, Ogun State College of Health Technology

    Department of Water Resources Management and Sanitation, Ogun State College of Health Technology, Ilese-Ijebu, NIGERIA

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Published

2016-06-30

Issue

Vol. 3 No. 1 (2016): January - June Issue

Section

Peer-reviewed Article

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How to Cite

Babatunde, A. M. Y. ., Kasim, L. S. ., & Ayoade, A. A. . (2016). Antimicrobial Study of Oil and Stem Bark Extracts of Pentaclethra Macrophylla Benth on Six Selected Pathogens. Malaysian Journal of Medical and Biological Research, 3(1), 7-10. https://doi.org/10.18034/mjmbr.v3i1.399
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