Blood Pressure is the Strongest Component Associated with Arterial Stiffness in Mexican Patients with Metabolic Syndrome

  • Ernesto G Cardona Muñoz University of Guadalajara
  • Fernando Grover Páez University of Guadalajara
  • Carlos G Ramos Becerra University of Guadalajara
  • Guillermo A Alanis Sánchez University of Guadalajara
  • Assen Ognianov Iantchoulev University of Guadalajara
  • David Cardona Müller University of Guadalajara
  • Sylvia E Totsuka Sutto University of Guadalajara
  • Sara Pascoe González University of Guadalajara
Keywords: Arterial stiffness, blood pressure, cardiovascular disease, metabolic syndrome, brachial-ankle pulse wave velocity, pulse, pressure

Abstract

To establish which of the metabolic syndrome (MetS) components are more related to arterial stiffness. We recruited eighty-two non-smoking male patients, 40 to 77 years old, (42 without MetS and 41 with MetS). The local ethics committee approved the study and signed informed consent forms were obtained from patients. Body mass index (BMI) was calculated as weight (in kilograms) divided by the square of height (in meters), and waist measurements were according to WHO recommendations. Blood pressure and baPWV were measured with the “Vascular Profiler 1000” device (VP-1000) (Omron®, Kyoto, Japan). All blood sample determinations were obtained after a 12-h fasting period and processed within one h. We used an oxidase technique to measure fasting plasma glucose (FPG) and enzymatic methods to obtain total cholesterol, high-density lipoprotein cholesterol (HDL-c) and triglyceride values. Low-density lipoprotein cholesterol (LDL-c) was estimated using the Friedewald formula (LDL-C = Total Cholesterol − HDL-C − Triglycerides/5). We observed strong and significant correlations between SBP and baPWV (r=.753, p=<0.001), and between SBP and PP (r=.853, p=<0.001). The remaining components did not correlate with baPWV or PP.

Downloads

Download data is not yet available.

Author Biographies

Ernesto G Cardona Muñoz, University of Guadalajara

Institute of Experimental and Clinical Therapeutics, Department of Physiology, University Center for Health Sciences, University of Guadalajara, MEXICO

Fernando Grover Páez, University of Guadalajara

Institute of Experimental and Clinical Therapeutics, Department of Physiology, University Center for Health Sciences, University of Guadalajara, MEXICO

Carlos G Ramos Becerra, University of Guadalajara

Institute of Experimental and Clinical Therapeutics, Department of Physiology, University Center for Health Sciences, University of Guadalajara, MEXICO

Guillermo A Alanis Sánchez, University of Guadalajara

Institute of Experimental and Clinical Therapeutics, Department of Physiology, University Center for Health Sciences, University of Guadalajara, MEXICO

Assen Ognianov Iantchoulev, University of Guadalajara

Institute of Experimental and Clinical Therapeutics, Department of Physiology, University Center for Health Sciences, University of Guadalajara, MEXICO

David Cardona Müller, University of Guadalajara

Institute of Experimental and Clinical Therapeutics, Department of Physiology, University Center for Health Sciences, University of Guadalajara, MEXICO

Sylvia E Totsuka Sutto, University of Guadalajara

Institute of Experimental and Clinical Therapeutics, Department of Physiology, University Center for Health Sciences, University of Guadalajara, MEXICO

Sara Pascoe González, University of Guadalajara

Institute of Experimental and Clinical Therapeutics, Department of Physiology, University Center for Health Sciences, University of Guadalajara, MEXICO

References

Allison MA, Budoff MJ, Wong ND, et al. (2008) Prevalence of and risk factors for subclinical cardiovascular disease in selected US Hispanic ethnic groups.Am J Epidemiol. 167. P. 962–969.

Barquera, S. Campos Nonato, I. Hernández-Barrera, et al. (2013) Prevalencia de obesidad en adultos mexicanos, ENSANUT 2012. Salud Pública Mex 55 Supl 2. P.S151-S160.

Chen L, Zhu W, Mai L, et al.(2015) The association of metabolic syndrome and its components with brachial-ankle pulse wave velocity in South China. Atherosclerosis. 240. P. 345–350.

Cho SK, Cho SK, Kim KH, et al. (2015) Effects of Age on Arterial Stiffness and Blood Pressure Variables in Patients with Newly Diagnosed Untreated Hypertension. Korean Circ J. 45. P. 44–50.

Gibbons GH, Dzau VJ. (1994) The emerging concept of vascular remodeling.N Engl J Med. 330. P. 1431–1438.

Laurent S, Boutouyrie P, Asmar R, et al. (2001) Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients. Hypertension. 37. 1236–1241.

Laurent S, Cockcroft J, Van Bortel L, et al. (2006) Expert consensus document on arterial stiffness: Methodological issues and clinical applications. Eur Heart J. 27. P. 2588–2605.

Quevedo KK. (2012) Aortic stiffness, blood pressure progression, and incident hypertension. Cardiol Rev.9. P. 875-81.

Scuteri A, Cunha PG, Rosei EA, et al. (2014) Arterial stiffness and influences of the metabolic syndrome: A cross-countries study. Atherosclerosis. 233. p. 654–660.

Tanaka H, Munakata M, Kawano Y, et al.(2009) Comparison between carotid-femoral and brachial-ankle pulse wave velocity as measures of arterial stiffness. J Hypertens.27.p 2022–2027.

Yamashina A, Tomiyama H, Takeda K, et al. (2002) Validity, reproducibility, and clinical significance of noninvasive brachial-ankle pulse wave velocity measurement. Hypertens Res. 25. 359–364.

--0--

Published
2015-12-17
How to Cite
MuñozE. G. C., PáezF. G., Becerra, C. G. R., SánchezG. A. A., Iantchoulev, A. O., Müller, D. C., Sutto, S. E. T. and González, S. P. (2015) “Blood Pressure is the Strongest Component Associated with Arterial Stiffness in Mexican Patients with Metabolic Syndrome”, ABC Journal of Advanced Research, 4(2), pp. 129-132. Available at: https://i-proclaim.my/journals/index.php/abcjar/article/view/38 (Accessed: 22July2019).
Section
Articles
Bookmark and Share

Most read articles by the same author(s)