Blood Pressure is the Strongest Component Associated with Arterial Stiffness in Mexican Patients with Metabolic Syndrome

Authors

  • Ernesto G Cardona Muñoz University of Guadalajara
  • Fernando Grover Páez University of Guadalajara
  • Carlos G Ramos Becerra University of Guadalajara
  • Guillermo A Alanis Sánchez University of Guadalajara
  • Assen Ognianov Iantchoulev University of Guadalajara
  • David Cardona Müller University of Guadalajara
  • Sylvia E Totsuka Sutto University of Guadalajara
  • Sara Pascoe González University of Guadalajara

DOI:

https://doi.org/10.18034/abcjar.v4i2.52

Keywords:

Arterial stiffness, blood pressure, cardiovascular disease, metabolic syndrome, brachial-ankle pulse wave velocity, pulse, pressure

Abstract

Objective: To establish which of the metabolic syndrome (MetS) components are more related to arterial stiffness. Research Design and Methods: We recruited eighty-two non-smoking male patients, 40 to 77 years old, (42 without MetS and 41 with MetS). The local ethics committee approved the study and signed informed consent forms were obtained from patients. Body mass index (BMI) was calculated as weight (in kilograms) divided by the square of height (in meters), and waist measurements were according to WHO recommendations. Blood pressure and baPWV were measured with the “Vascular Profiler 1000” device (VP-1000) (Omron®, Kyoto, Japan). All blood sample determinations were obtained after a 12-h fasting period and processed within one h. We used an oxidase technique to measure fasting plasma glucose (FPG) and enzymatic methods to obtain total cholesterol, high-density lipoprotein cholesterol (HDL-c) and triglyceride values. Low-density lipoprotein cholesterol (LDL-c) was estimated using the Friedewald formula (LDL-C = Total Cholesterol − HDL-C − Triglycerides/5). Results: We observed strong and significant correlations between SBP and baPWV (r=.753, p=<0.001), and between SBP and PP (r=.853, p=<0.001). The remaining components did not correlate with baPWV or PP.

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Author Biographies

  • Ernesto G Cardona Muñoz, University of Guadalajara

    Institute of Experimental and Clinical Therapeutics, Department of Physiology, University Center for Health Sciences, University of Guadalajara, MEXICO

  • Fernando Grover Páez, University of Guadalajara

    Institute of Experimental and Clinical Therapeutics, Department of Physiology, University Center for Health Sciences, University of Guadalajara, MEXICO

     
  • Carlos G Ramos Becerra, University of Guadalajara

    Institute of Experimental and Clinical Therapeutics, Department of Physiology, University Center for Health Sciences, University of Guadalajara, MEXICO

     
  • Guillermo A Alanis Sánchez, University of Guadalajara

    Institute of Experimental and Clinical Therapeutics, Department of Physiology, University Center for Health Sciences, University of Guadalajara, MEXICO

     

     
  • Assen Ognianov Iantchoulev, University of Guadalajara

    Institute of Experimental and Clinical Therapeutics, Department of Physiology, University Center for Health Sciences, University of Guadalajara, MEXICO

  • David Cardona Müller, University of Guadalajara

    Institute of Experimental and Clinical Therapeutics, Department of Physiology, University Center for Health Sciences, University of Guadalajara, MEXICO

     

  • Sylvia E Totsuka Sutto, University of Guadalajara

    Institute of Experimental and Clinical Therapeutics, Department of Physiology, University Center for Health Sciences, University of Guadalajara, MEXICO

     
  • Sara Pascoe González, University of Guadalajara

    Institute of Experimental and Clinical Therapeutics, Department of Physiology, University Center for Health Sciences, University of Guadalajara, MEXICO

     

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Published

2015-12-31

Issue

Vol. 4 No. 2 (2015): July-December

Section

Articles

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How to Cite

Muñoz E. G. C. ., Páez F. G. ., Becerra, C. G. R. ., Sánchez G. A. A. ., Iantchoulev, A. O. ., Müller, D. C. ., Sutto, S. E. T. ., & González, S. P. . (2015). Blood Pressure is the Strongest Component Associated with Arterial Stiffness in Mexican Patients with Metabolic Syndrome. ABC Journal of Advanced Research, 4(2), 129-132. https://doi.org/10.18034/abcjar.v4i2.52
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